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Sanctuary is an area first introduced in Monster Hunter 4. It is an isolated, arena-like zone located somewhere between the Ancestral Steppe and the Heaven's Mount. It is characterized by its rocky outcroppings, fractured ground, and long, dry grass. This area is home to extremely powerful monsters such as Shagaru Magala and Rajang.
- This area shares a base camp with the Heaven's Mount. However, the entrance to the Heaven's Mount is blocked by a large boulder.
- According to the Cathar Elder, it is the original location for the outbreak of the Frenzy Virus.