Number of Monsters - Comparison with Previous Games
- Every Monster from Monster Hunter G are returning in this game.
- 21 new monsters are in the game; 8 Small monsters and 16 Large Monsters.
- 1 New Neopteron: Great Thunderbug.
- 2 New Herbivores: Popo and Anteka.
- 1 New Flying Wyvern: Remobra.
- 7 New Elder Dragons: Kushala Daora and Rusted Kushala Daora, the game's flagship monsters, Chameleos, Teostra, White Fatalis, Lunastra, the Offline end-game monster, and Yama Tsukami, the Online end-game monster.
- A large Shakalaka is first seen in this game. Though not classified as a Large Monster in this game, it becomes a boss and is given a name in the later series.
- Kirin and Lao-Shan Lung became available to hunt Offline in this game. Fatalis remained Online only.
- Lunastra is an Offline-Exclusive monster, while Shen Gaoren, Rajang, Ashen Lao-Shan Lung, Fatalis, Crimson Fatalis, White Fatalis and Yama Tsukami are Online-Exclusive monsters in this game.