They are significantly larger than normal Ioprey and possess a larger crest. Unlike other 'dromes, Iodromes have a more amphibian look, with salamander-like skin that seems to glisten with moisture, and frog-like throat sacs. They also lack the sharp claws of their raptor relatives, relying more on poison to bring down prey and enemies.
Iodromes present a good challenge for beginner hunters. Although not as strong as Flying Wyverns, they can quickly cripple hunters with the power of their numbers and poison. Iodromes are a threat due to their speed, agility, considerable strength and poison.
When threatened, Iodromes spit Poison from the poison sac in their throat.
Iodromes are the leader of a pack of Ioprey, and always travel with their pack for protection.
In a CG video, Iodrome is seen commanding a pack of Ioprey to attack a Zinogre. They almost succeed in killing it, but Zinogre succumbs to the Frenzy Virus and ravages the Iodrome, who is promptly killed and devoured by its own pack, now also infected by the virus.
Iodrome can be kept as a pet.
HR100 Iodrome's have been seen travel in pairs, following each other closely through different areas.
G-Rank Iodrome gains a few new attacks; an improved bite that releases poison and a improved poison spit where after the projectile touches the ground it forms a toxic puddle that eventually fades away. Other new attacks include a high speed charge and a jump in air whilst spitting poison move, always followed by landing and delivering an uppercut that launches hunters.
Iodrome can be attacked by Baruragaru mid-quest; if it succumbs to the attack, Baruragaru will subsequently be able to use poison-based attacks.